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Recombinant Human CDC73 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CDC73-3933H
Product Overview : CDC73 MS Standard C13 and N15-labeled recombinant protein (NP_078805) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 60.6 kDa
AA Sequence : MADVLSVLRQYNIQKKEIVVKGDEV IFGEFSWPKNVKTNYVVWGTGKEGQ PREYYTLDSILFLLNNVHLSHPVYV RRAATENIPVVRRPDRKDLLGYLNG EASTSASIDRSAPLEIGLQRSTQVK RAADEVLAEAKKPRIEDEECVRLDK ERLAARLEGHKEGIVQTEQIRSLSE AMSVEKIAAIKAKIMAKKRSTIKTD LDDDITALKQRSFVDAEVDVTRDIV SRERVWRTRTTILQSTGKNFSKNIF AILQSVKAREEGRAPEQRPAPNAAP VDPTLRTKQPIPAAYNRYDQERFKG KEETEGFKIDTMGTYHGMTLKSVTE GASARKTQTPAAQPVPRPVSQARPP PNQKKGSRTPIIIIPAATTSLITML NAKDLLQDLKFVPSDEKKKQGCQRE NETLIQRRKDQMQPGGTAISVTVPY RVVDQPLKLMPQDWDRVVAVFVQGP AWQFKGWPWLLPDGSPVDIFAKIKA FHLKYDEVRLDPNVQKWDVTVLELS YHKRHLDRPVFLRFWETLDRYMVKH KSHLRFTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CDC73 cell division cycle 73 [ Homo sapiens (human) ]
Official Symbol : CDC73
Synonyms : CDC73; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); C1orf28, chromosome 1 open reading frame 28, HRPT2, hyperparathyroidism 2 (with jaw tumor); parafibromin; hyperparathyroidism 2 protein; cell division cycle protein 73 homolog; HYX; HPTJT; HRPT2; C1orf28; FLJ23316;
Gene ID : 79577
mRNA Refseq : NM_024529
Protein Refseq : NP_078805
MIM : 607393
UniProt ID : Q6P1J9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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