Recombinant Human CELF6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CELF6-2205H
• Product Overview: CELF6 MS Standard C13 and N15-labeled recombinant protein (NP_443072) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50.5 kDa
• AA Sequence: MTAAPGGSAQPAGPGPRLGFSTADS GVGMSGLNPGPAVPMKDHDAIKLFV GQIPRGLDEQDLKPLFEEFGRIYEL TVLKDRLTGLHKGCAFLTYCARDSA LKAQSALHEQKTLPGMNRPIQVKPA ASEGRGEDRKLFVGMLGKQQGEEDV RRLFQPFGHIEECTVLRSPDGTSKG CAFVKFGSQGEAQAAIRGLHGSRTM AGASSSLVVKLADTDRERALRRMQQ MAGHLGAFHPAPLPLGACGAYTTAI LQHQAALLAAAQGPGLGPVAAVAAQ MQHVAAFSLVAAPLLPAAAANSPPG SGPGTLPGLPAPIGVNGFGPLTPQT NGQPGSDTLYNNGLSPYPAQSPGVA DPLQQAYAGMHHYAAAYPSAYAPVS TAFPQQPSALPQQQREGPEGCNLFI YHLPQEFGDAELIQTFLPFGAVVSA KVFVDRATNQSKCFGFVSFDNPTSA QTAIQAMNGFQIGMKRLKAQLKRPK DANRPYTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CELF6 CUGBP Elav-like family member 6 [ Homo sapiens (human) ]
• Official Symbol: CELF6
• Synonyms: CELF6; CUGBP Elav-like family member 6; BRUNOL6; CUGBP Elav-like family member 6; Bruno -like 6, RNA binding protein; CELF-6; CUG-BP- and ETR-3-like factor 6; RNA-binding protein BRUNOL-6; bruno-like 6, RNA binding protein; bruno-like protein 6; EC 3.2.1.52
• Gene ID: 60677
• mRNA Refseq: NM_052840
• Protein Refseq: NP_443072
• MIM: 612681
• UniProt ID: Q96J87