| Description : |
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
66.9 kDa |
| AA Sequence : |
MTAQSRSPTTPTFPGPSQRTPLTPC PVQTPRLGKALIHCWTDPGQPLGEQ QRVRRQRTETSEPTMRLHRLRARLS AVACGLLLLLVRGQGQDSASPIRTT HTGQVLGSLVHVKGANAGVQTFLGI PFAKPPLGPLRFAPPEPPESWSGVR DGTTHPAMCLQDLTAVESEFLSQFN MTFPSDSMSEDCLYLSIYTPAHSHE GSNLPVMVWIHGGALVFGMASLYDG SMLAALENVVVVIIQYRLGVLGFFS TGDKHATGNWGYLDQVAALRWVQQN IAHFGGNPDRVTIFGESAGGTSVSS LVVSPISQGLFHGAIMESGVALLPG LIASSADVISTVVANLSACDQVDSE ALVGCLRGKSKEEILAINKPFKMIP GVVDGVFLPRHPQELLASADFQPVP SIVGVNNNEFGWLIPKVMRIYDTQK EMDREASQAALQKMLTLLMLPPTFG DLLREEYIGDNGDPQTLQAQFQEMM ADSMFVIPALQVAHFQCSRAPVYFY EFQHQPSWLKNIRPPHMKADHVKFT EEEEQLSRKMMKYWANFARNGNPNG EGLPHWPLFDQEEQYLQLNLQPAVG RALKAHRLQFWKKALPQKIQELEEP EERHTELTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
