Recombinant Human Chemokine (C-X-C Motif) Ligand 1, His-tagged
|Product Overview :||Recombinant Human Chemokine (C-X-C Motif) Ligand 1 encoding the human GRO-alpha/CXCL1(1-73) (Ala1-Asn73) was expressed inE.Coli, It was recombined with a Hexa-his tag at the N-Terminus and purified by Ni-NTA column. MW=8.0 KD.|
- Gene Information
- Related Products
|Cat. No. :||CXCL1-88H|
|Description :||Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene.|
|Sequence :||Human GRO-alpha/CXCL1(1-73) (Ala1-Asn73)1 ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPA SPIVK KIIEKMLNSD KSN 73|
|Formulation :||Lyophilized 100μg human GRO-alpha/CXCL1 (1-73) 1 in 50μl of TBS (20mM Tris, 50mM NaCl, pH8.0). Carry free.|
|Purity :||>95% by SDS gel.|
|Application :||Cell biology.|
|Reconstitution :||Add 500μl deionized water to the vial to prepare a working stock solution at 200μg/mL. Allow to set at least 30 minutes at 4℃, mix well.|
|Storage :||Store lyophilized protein at -20℃ or -70℃. Lyophilized protein is stable for up to 6 months from date of receipt at -20℃ to -70℃. Upon reconstitution, this protein can be stored at -20℃ for a few weeks or at -70℃ in a manual defrost freezer for long term storage (six months). Aliquot reconstituted protein to avoid repeated freezing / thawing cycles.|
|Gene Name :||CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [ Homo sapiens ]|
|Synonyms :||FSP; GRO; GRO1; GROA; GROa; MGSA; MGSA-a; NAP-3; SCYB1; MGSA alpha; C-X-C motif chemokine 1; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); Melanoma growth stimulatory activity; Neutrophil-activating protein 3; chemokine (C-X-C motif) ligand 1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein; melanoma growth stimulatory activity alpha; GROA_HUMAN; Growth-regulated alpha protein [Precursor]; GRO-alpha(1-73); CXCL1|
|Gene ID :||2919|
|mRNA Refseq :||NM_001511|
|Protein Refseq :||NP_001502|
|UniProt ID :||P09341|
|Chromosome Location :||4q21|
|Pathway :||Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection|
|Function :||chemokine activity; enzyme activator activity; growth factor activity|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (7)Ask a question
Therapeutic strategies targeting CXCL1 aim to modulate its activity in diseases like cancer and chronic inflammation.
It mediates inflammation by promoting leukocyte migration and activation.
In cancer, CXCL1 can promote tumor growth, metastasis, and angiogenesis.
CXCL1 contributes to angiogenesis, supporting new blood vessel formation.
CXCL1 is a chemokine that attracts neutrophils to sites of infection or injury.
CXCL1 levels are elevated in conditions like cancer, inflammatory diseases, and infections.
CXCL1 expression is regulated by various stimuli, including cytokines and growth factors.
Customer Reviews (3)Write a review
Efficient delivery, great service. -
Product as described, perfect. -
Reliable for protein work. -
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