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Recombinant Human CHMP4A Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CHMP4A-6331H
Product Overview : CHMP4A MS Standard C13 and N15-labeled recombinant protein (NP_054888) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 29.8 kDa
AA Sequence : MSRRRPEDGLGKAGPCVMRHHPPRS KAEVWRTLRGGGGRGELAMSGLGRL FGKGKKEKGPTPEEAIQKLKETEKI LIKKQEFLEQKIQQELQTAKKYGTK NKRAALQALRRKKRFEQQLAQTDGT LSTLEFQREAIENATTNAEVLRTME LAAQSMKKAYQDMDIDKVDELMTDI TEQQEVAQQISDAISRPMGFGDDVD EDELLEELEELEQEELAQELLNVGD KEEEPSVKLPSVPSTHLPAGPAPKV DEDEEALKQLAEWVSTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CHMP4A charged multivesicular body protein 4A [ Homo sapiens (human) ]
Official Symbol : CHMP4A
Synonyms : CHMP4A; charged multivesicular body protein 4A; C14orf123, chromatin modifying protein 4A, chromosome 14 open reading frame 123; charged multivesicular body protein 4a; HSPC134; VPS32A; chromatin modifying protein 4A; SNF7 homolog associated with Alix-2; Snf7 homologue associated with Alix 2; vacuolar protein sorting-associated protein 32-1; SNF7; CHMP4; SHAX2; CHMP4B; SNF7-1; VPS32-1; C14orf123; FLJ61658; MGC142093; MGC142095;
Gene ID : 29082
mRNA Refseq : NM_014169
Protein Refseq : NP_054888
MIM : 610051
UniProt ID : Q9BY43

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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