Recombinant Human CHST15 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CHST15-1878H
• Product Overview: CHST15 MS Standard C13 and N15-labeled recombinant protein (NP_056976) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 64.9 kDa
• AA Sequence: MRHCINCCIQLLPDGAHKQQVNCQG GPHHGHQACPTCKGENKILFRVDSK QMNLLAVLEVRTEGNENWGGFLRFK KGKRCSLVFGLIIMTLVMASYILSG AHQELLISSPFHYGGFPSNPSLMDS ENPSDTKEHHHQSSVNNISYMKDYP SIKLIINSITTRIEFTTRQLPDLED LKKQELHMFSVIPNKFLPNSKSPCW YEEFSGQNTTDPYLTNSYVLYSKRF RSTFDALRKAFWGHLAHAHGKHFRL RCLPHFYIIGQPKCGTTDLYDRLRL HPEVKFSAIKEPHWWTRKRFGIVRL RDGLRDRYPVEDYLDLFDLAAHQIH QGLQASSAKEQSKMNTIIIGEASAS TMWDNNAWTFFYDNSTDGEPPFLTQ DFIHAFQPNARLIVMLRDPVERLYS DYLYFASSNKSADDFHEKVTEALQL FENCMLDYSLRACVYNNTLNNAMPV RLQVGLYAVYLLDWLSVFDKQQFLI LRLEDHASNVKYTMHKVFQFLNLGP LSEKQEALMTKSPASNARRPEDRNL GPMWPITQKILRDFYRPFNARLAQV LADEAFAWKTTTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CHST15 carbohydrate sulfotransferase 15 [ Homo sapiens (human) ]
• Official Symbol: CHST15
• Synonyms: CHST15; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; carbohydrate sulfotransferase 15; B cell RAG associated protein; BRAG; GALNAC4S 6ST; KIAA0598; N acetylgalactosamine 4 sulfate 6 O sulfotransferase; hBRAG; B-cell RAG-associated gene protein; B cell RAG associated protein (GALNAC4S-6ST); N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; GALNAC4S-6ST; RP11-47G11.1; MGC34346; DKFZp781H1369
• Gene ID: 51363
• mRNA Refseq: NM_015892
• Protein Refseq: NP_056976
• MIM: 608277
• UniProt ID: Q7LFX5