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Recombinant Human CKB protein, His-tagged

Cat.No. : CKB-344H
Product Overview : Recombinant Human CKB protein (Pro2-Lys381), fused to His tag at N-terminus, was expressed in E.coli.
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  • Gene Information
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Description : Creatine kinase B-type (CKB) is also known as Creatine kinase B chain, B-CK and CKBB. CKB consists of a homodimer of two identical brain-type CK-B subunits. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Furthermore, ectopic expression of the CKB in red cells and platelets is a rare, benign anomaly detected during a newborn screening program for Duchenne muscular dystrophy.
Source : E.coli
Species : Human
Tag : His
Form : Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 43.5 kDa. The protein migrates as 45 kDa under reducing (R) condition (SDS-PAGE).
Protein length : 380
Endotoxin : Less than 1.0 EU per ug by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : CKB
Official Symbol : CKB
Synonyms : CKB; creatine kinase, brain; CKBB; creatine kinase B-type; creatine kinase-B; creatine kinase B chain; B-CK
Gene ID : 1152
mRNA Refseq : NM_001823
Protein Refseq : NP_001814
MIM : 123280
UniProt ID : P12277

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any other clinical markers that work in conjunction with CKB in muscle disease diagnosis? 09/18/2022

Yes, alongside CKB, other markers like Troponin and myoglobin are used to diagnose and assess muscle injuries.

What are some of the potential clinical applications of CKB protein? 01/19/2022

CKB has applications in diagnosing and monitoring neurological and muscle disorders.

How is CKB protein clinically significant? 08/10/2019

CKB protein is clinically significant because it plays a crucial role in energy metabolism in tissues like the brain.

How is CKB protein used in the diagnosis of brain-related conditions? 08/26/2018

Elevated levels of CKB in cerebrospinal fluid can indicate brain injury or neurodegenerative diseases.

Can CKB protein levels be used to monitor treatment effectiveness in muscle-related conditions? 07/05/2018

Yes, CKB levels can be monitored to assess the progress of treatment in muscle disorders.

Customer Reviews (3)

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Reviews
12/21/2020

    Highly recommended for its exceptional performance in ELISA, the CKB protein is a top contender for researchers involved in protein electron microscopy structure analysis.

    08/24/2020

      Coupled with the manufacturer's exceptional technical support and commitment to customer satisfaction, researchers can confidently utilize the CKB protein in their studies, knowing that they have the necessary resources and assistance to succeed.

      07/19/2018

        Its remarkable attributes and consistent results make it an indispensable tool in various experimental applications.

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