Recombinant Human CKB protein, His-tagged
Cat.No. : | CKB-344H |
Product Overview : | Recombinant Human CKB protein (Pro2-Lys381), fused to His tag at N-terminus, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | Creatine kinase B-type (CKB) is also known as Creatine kinase B chain, B-CK and CKBB. CKB consists of a homodimer of two identical brain-type CK-B subunits. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Furthermore, ectopic expression of the CKB in red cells and platelets is a rare, benign anomaly detected during a newborn screening program for Duchenne muscular dystrophy. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 43.5 kDa. The protein migrates as 45 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | 380 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CKB |
Official Symbol : | CKB |
Synonyms : | CKB; creatine kinase, brain; CKBB; creatine kinase B-type; creatine kinase-B; creatine kinase B chain; B-CK |
Gene ID : | 1152 |
mRNA Refseq : | NM_001823 |
Protein Refseq : | NP_001814 |
MIM : | 123280 |
UniProt ID : | P12277 |
Products Types
◆ Recombinant Protein | ||
CKB-1391H | Recombinant Human CKB Protein, GST-tagged | +Inquiry |
Ckb-895M | Recombinant Mouse Ckb Protein, MYC/DDK-tagged | +Inquiry |
CKB-607H | Recombinant Human CKB Protein, His (Fc)-Avi-tagged | +Inquiry |
CKB-710R | Recombinant Rhesus Macaque CKB Protein, His (Fc)-Avi-tagged | +Inquiry |
CKB-792H | Recombinant Human CKB Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
CKB-46M | Native Mouse Creatine Kinase, Brain (CKB) Protein | +Inquiry |
CKB-1177H | Native Human Creatine Kinase, Brain | +Inquiry |
CKB-8079H | Active Native Human CKB protein | +Inquiry |
◆ Lysates | ||
CKB-001HCL | Recombinant Human CKB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, alongside CKB, other markers like Troponin and myoglobin are used to diagnose and assess muscle injuries.
CKB has applications in diagnosing and monitoring neurological and muscle disorders.
CKB protein is clinically significant because it plays a crucial role in energy metabolism in tissues like the brain.
Elevated levels of CKB in cerebrospinal fluid can indicate brain injury or neurodegenerative diseases.
Yes, CKB levels can be monitored to assess the progress of treatment in muscle disorders.
Customer Reviews (3)
Write a reviewHighly recommended for its exceptional performance in ELISA, the CKB protein is a top contender for researchers involved in protein electron microscopy structure analysis.
Coupled with the manufacturer's exceptional technical support and commitment to customer satisfaction, researchers can confidently utilize the CKB protein in their studies, knowing that they have the necessary resources and assistance to succeed.
Its remarkable attributes and consistent results make it an indispensable tool in various experimental applications.
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