| Description : |
This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
141.72 kDa |
| AA Sequence : |
MAPRRNNGQCWCLLMLLSVSTPLPA VTQTRGATETASQGHLDLTQLIGVP LPSSVSFVTGYGGFPAYSFGPGANV GRPARTLIPSTFFRDFAISVVVKPS STRGGVLFAITDAFQKVIYLGLRLS GVEDGHQRIILYYTEPGSHVSQEAA AFSVPVMTHRWNRFAMIVQGEEVTL LVNCEEHSRIPFQRSSQALAFESSA GIFMGNAGATGLERFTGSLQQLTVH PDPRTPEELCDPEESSASGETSGLQ EADGVAEILEAVTYTQASPKEAKVE PINTPPTPSSPFEDMELSGEPVPEG TLETTNMSIIQHSSPKQGSGEILND TLEGVHSVDGDPITDSGSGAGAFLD IAEEKNLAATAAGLAEVPISTAGEA EASSVPTGGPTLSMSTENPEEGVTP GPDNEERLAATAAGEAEALASMPGE VEASGVAPGELDLSMSAQSLGEEAT VGPSSEDSLTTAAAATEVSLSTFED EEASGVPTDGLAPLTATMAPERAVT SGPGDEEDLAAATTEEPLITAGGEE SGSPPPDGPPLPLPTVAPERWITPA QREHVGMKGQAGPKGEKGDAGEELP GPPEPSGPVGPTAGAEAEGSGLGWG SDVGSGSGDLVGSEQLLRGPPGPPG PPGLPGIPGKPGTDVFMGPPGSPGE DGPAGEPGPPGPEGQPGVDGATGLP GMKGEKGARGPNGSVGEKGDPGNRG LPGPPGKKGQAGPPGVMGPPGPPGP PGPPGPGCTMGLGFEDTEGSGSTQL LNEPKLSRPTAAIGLKGEKGDRGPK GERGMDGASIVGPPGPRGPPGHIKV LSNSLINITHGFMNFSDIPELVGPP GPDGLPGLPGFPGPRGPKGDTGLPG FPGLKGEQGEKGEPGAILTEDIPLE RLMGKKGEPGMHGAPGPMGPKGPPG HKGEFGLPGRPGRPGLNGLKGTKGD PGVIMQGPPGLPGPPGPPGPPGAVI NIKGAIFPIPVRPHCKMPVDTAHPG SPELITFHGVKGEKGSWGLPGSKGE KGDQGAQGPPGPPLDLAYLRHFLNN LKGENGDKGFKGEKGEKGDINGSFL MSGPPGLPGNPGPAGQKGETVVGPQ GPPGAPGLPGPPGFGRPGDPGPPGP PGPPGPPAILGAAVALPGPPGPPGQ PGLPGSRNLVTAFSNMDDMLQKAHL VIEGTFIYLRDSTEFFIRVRDGWKK LQLGELIPIPADSPPPPALSSNPHQ LLPPPNPISSANYEKPALHLAALNM PFSGDIRADFQCFKQARAAGLLSTY RAFLSSHLQDLSTIVRKAERYSLPI VNLKGQVLFNNWDSIFSGHGGQFNM HIPIYSFDGRDIMTDPSWPQKVIWH GSSPHGVRLVDNYCEAWRTADTAVT GLASPLSTGKILDQKAYSCANRLIV LCIENSFMTDARKTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
