| Description : |
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
108.5 kDa |
| AA Sequence : |
MRAARALLPLLLQACWTAAQDEPET PRAVAFQDCPVDLFFVLDTSESVAL RLKPYGALVDKVKSFTKRFIDNLRD RYYRCDRNLVWNAGALHYSDEVEII QGLTRMPGGRDALKSSVDAVKYFGK GTYTDCAIKKGLEQLLVGGSHLKEN KYLIVVTDGHPLEGYKEPCGGLEDA VNEAKHLGVKVFSVAITPDHLEPRL SIIATDHTYRRNFTAADWGQSRDAE EAISQTIDTIVDMIKNNVEQVCCSF ECQPARGPPGLRGDPGFEGERGKPG LPGEKGEAGDPGRPGDLGPVGYQGM KGEKGSRGEKGSRGPKGYKGEKGKR GIDGVDGVKGEMGYPGLPGCKGSPG FDGIQGPPGPKGDPGAFGLKGEKGE PGADGEAGRPGSSGPSGDEGQPGEP GPPGEKGEAGDEGNPGPDGAPGERG GPGERGPRGTPGTRGPRGDPGEAGP QGDQGREGPVGVPGDPGEAGPIGPK GYRGDEGPPGSEGARGAPGPAGPPG DPGLMGERGEDGPAGNGTEGFPGFP GYPGNRGAPGINGTKGYPGLKGDEG EAGDPGDDNNDIAPRGVKGAKGYRG PEGPQGPPGHQGPPGPDECEILDII MKMCSCCECKCGPIDLLFVLDSSES IGLQNFEIAKDFVVKVIDRLSRDEL VKFEPGQSYAGVVQYSHSQMQEHVS LRSPSIRNVQELKEAIKSLQWMAGG TFTGEALQYTRDQLLPPSPNNRIAL VITDGRSDTQRDTTPLNVLCSPGIQ VVSVGIKDVFDFIPGSDQLNVISCQ GLAPSQGRPGLSLVKENYAELLEDA FLKNVTAQICIDKKCPDYTCPITFS SPADITILLDGSASVGSHNFDTTKR FAKRLAERFLTAGRTDPAHDVRVAV VQYSGTGQQRPERASLQFLQNYTAL ASAVDAMDFINDATDVNDALGYVTR FYREASSGAAKKRLLLFSDGNSQGA TPAAIEKAVQEAQRAGIEIFVVVVG RQVNEPHIRVLVTGKTAEYDVAYGE SHLFRVPSYQALLRGVFHQTVSRKV ALGTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
