Recombinant Human CORO7 Protein, MYC/DDK-tagged

• Cat.No.: CORO7-3305H
• Product Overview: Recombinant Human CORO7 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants; some of which form read-through transcripts with a neighboring gene.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 100.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CORO7 coronin 7 [ Homo sapiens ]
• Official Symbol: CORO7
• Synonyms: 0610011B16Rik; CRN7; POD1
• Gene ID: 79585
• mRNA Refseq: NM_024535.4
• Protein Refseq: NP_078811
• MIM: 611668