Recombinant Human CPT1A Protein, DYKDDDDK-tagged

• Cat.No.: CPT1A-01H
• Product Overview: Recombinant protein from the full-length sequence of Homo sapiens carnitine palmitoyltransferase 1A (CPT1A), transcript variant 1 (NM_001876), with a DYKDDDDK tag was expressed inn human cells.

Specification

• Description: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: Human Cells
• Species: Human
• Tag: DYKDDDDK
• Molecular Mass: 88.2 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/μg of protein (<1EU/μg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Gene Information

• Gene Name: CPT1A carnitine palmitoyltransferase 1A [ Homo sapiens (human) ]
• Official Symbol: CPT1A
• Synonyms: CPT1A; carnitine palmitoyltransferase 1A; CPT1; CPT1-L; L-CPT1; carnitine O-palmitoyltransferase 1, liver isoform; CPT I; CPTI-L; carnitine palmitoyltransferase 1A (liver); carnitine palmitoyltransferase I, liver; EC 2.3.1.21
• Gene ID: 1374
• mRNA Refseq: NM_001876
• Protein Refseq: NP_001867
• MIM: 600528
• UniProt ID: P50416