| Description : |
This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
71.2 kDa |
| AA Sequence : |
MAPSADPGMSRMLPFLLLLWFLPIT EGSQRAEPMFTAVTNSVLPPDYDSN PTQLNYGVAVTDVDHDGDFEIVVAG YNGPNLVLKYDRAQKRLVNIAVDER SSPYYALRDRQGNAIGVTACDIDGD GREEIYFLNTNNAFSGVATYTDKLF KFRNNRWEDILSDEVNVARGVASLF AGRSVACVDRKGSGRYSIYIANYAY GNVGPDALIEMDPEASDLSRGILAL RDVAAEAGVSKYTGGRGVSVGPILS SSASDIFCDNENGPNFLFHNRGDGT FVDAAASAGVDDPHQHGRGVALADF NRDGKVDIVYGNWNGPHRLYLQMST HGKVRFRDIASPKFSMPSPVRTVIT ADFDNDQELEIFFNNIAYRSSSANR LFRVIRREHGDPLIEELNPGDALEP EGRGTGGVVTDFDGDGMLDLILSHG ESMAQPLSVFRGNQGFNNNWLRVVP RTRFGAFARGAKVVLYTKKSGAHLR IIDGGSGYLCEMEPVAHFGLGKDEA SSVEVTWPDGKMVSRNVASGEMNSV LEILYPRDEDTLQDPAPLECGQGFS QQENGHCMDTNECIQFPFVCPRDKP VCVNTYGSYRCRTNKKCSRGYEPNE DGTACVGTLGQSPGPRPTTPTAAAA TAAAAAAAGAATAAPVLVDGDLNLG SVVKESCEPSCTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
