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Recombinant Human CRY1 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CRY1-2082H
Product Overview : CRY1 MS Standard C13 and N15-labeled recombinant protein (NP_004066) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 66.4 kDa
AA Sequence : MGVNAVHWFRKGLRLHDNPALKECI QGADTIRCVYILDPWFAGSSNVGIN RWRFLLQCLEDLDANLRKLNSRLFV IRGQPADVFPRLFKEWNITKLSIEY DSEPFGKERDAAIKKLATEAGVEVI VRISHTLYDLDKIIELNGGQPPLTY KRFQTLISKMEPLEIPVETITSEVI EKCTTPLSDDHDEKYGVPSLEELGF DTDGLSSAVWPGGETEALTRLERHL ERKAWVANFERPRMNANSLLASPTG LSPYLRFGCLSCRLFYFKLTDLYKK VKKNSSPPLSLYGQLLWREFFYTAA TNNPRFDKMEGNPICVQIPWDKNPE ALAKWAEGRTGFPWIDAIMTQLRQE GWIHHLARHAVACFLTRGDLWISWE EGMKVFEELLLDADWSINAGSWMWL SCSSFFQQFFHCYCPVGFGRRTDPN GDYIRRYLPVLRGFPAKYIYDPWNA PEGIQKVAKCLIGVNYPKPMVNHAE ASRLNIERMKQIYQQLSRYRGLGLL ASVPSNPNGNGGFMGYSAENIPGCS SSGSCSQGSGILHYAHGDSQQTHLL KQGRSSMGTGLSGGKRPSQEEDTQS IGPKVQRQSTNTRTRPLEQKLISEE DLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CRY1 cryptochrome circadian regulator 1 [ Homo sapiens (human) ]
Official Symbol : CRY1
Synonyms : CRY1; cryptochrome 1 (photolyase-like); PHLL1; cryptochrome-1; photolyase-like cryptochrome 1;
Gene ID : 1407
mRNA Refseq : NM_004075
Protein Refseq : NP_004066
MIM : 601933
UniProt ID : Q16526

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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