Recombinant Human CST6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CST6-1094H
• Product Overview: CST6 MS Standard C13 and N15-labeled recombinant protein (NP_001314) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 16.5 kDa
• AA Sequence: MARSNLPLALGLALVAFCLLALPRD ARARPQERMVGELRDLSPDDPQVQK AAQAAVASYNMGSNSIYYFRDTHII KAQSQLVAGIKYFLTMEMGSTDCRK TRVTGDHVDLTTCPLAAGAQQEKLR CDFEVLVVPWQNSSQLLKHNCVQMT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CST6 cystatin E/M [ Homo sapiens (human) ]
• Official Symbol: CST6
• Synonyms: CST6; cystatin E/M; cystatin-M; cystatin 6; cystatin M; cystatin-6; cystatin-E; cystatin M/E; cysteine proteinase inhibitor
• Gene ID: 1474
• mRNA Refseq: NM_001323
• Protein Refseq: NP_001314
• MIM: 601891
• UniProt ID: Q15828