Active Recombinant Human CTSD protein, His-tagged
Cat.No. : | CTSD-04H |
Product Overview : | Recombinant Human CTSD protein, fused to His-tag, was expressed in HEK293. |
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- Gene Information
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Description : | This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Liquid in. 50mM MES buffer (pH 5.5) containing 100mM NaCl, 20% glycerol. |
Bio-activity : | Specific activity is > 20 pmol/min/ug, and is defined as the amount of enzyme that cleaves 1pmol of Mca-PLGL-Dpa-AR-NH2 per minute at pH 3.5 at 25 centigrade. |
Molecular Mass : | 43.4 kDa |
Protein length : | 21-412aa |
AA Sequence : | LVRIPLHKFT SIRRTMSEVG GSVEDLIAKG PVSKYSQAVP AVTEGPIPEV LKNYMDAQYY GEIGIGTPPQ CFTVVFDTGS SNLWVPSIHC KLLDIACWIH HKYNSDKSST YVKNGTSFDI HYGSGSLSGY LSQDTVSVPC QSASSASALG GVKVERQVFG EATKQPGITF IAAKFDGILG MAYPRISVNN VLPVFDNLMQ QKLVDQNIFS FYLSRDPDAQ PGGELMLGGT DSKYYKGSLS YLNVTRKAYW QVHLDQVEVA SGLTLCKEGC EAIVDTGTSL MVGPVDEVRE LQKAIGAVPL IQGEYMIPCE KVSTLPAITL KLGGKGYKLS PEDYTLKVSQ AGKTLCLSGF MGMDIPPPSG PLWILGDVFI GRYYTVFDRD NNRVGFAEAA RL |
Endotoxin : | < 1 EU per 1ug of protein (determined by LAL method). |
Purity : | > 95% |
Applications : | SDS-PAGE, Enzyme Activity |
Storage : | Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml |
Gene Name : | CTSD cathepsin D [ Homo sapiens (human) ] |
Official Symbol : | CTSD |
Synonyms : | CPSD; CTSD; Cathepsin D; CLN10; HEL-S-130P; lysosomal aspartyl protease; lysosomal aspartyl peptidase; lysosomal aspartyl protease |
Gene ID : | 1509 |
mRNA Refseq : | NM_001909 |
Protein Refseq : | NP_001900 |
MIM : | 116840 |
UniProt ID : | P07339 |
Products Types
◆ Recombinant Protein | ||
CTSD-435C | Recombinant Cricetulus Griseus CTSD Protein (65-408 aa), His-SUMO-tagged | +Inquiry |
Ctsd-2369M | Recombinant Mouse Ctsd Protein, His-tagged | +Inquiry |
CTSD-2582H | Recombinant Human CTSD protein(71-410 aa), C-His-tagged | +Inquiry |
CTSD-913R | Recombinant Rhesus Macaque CTSD Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSD-786H | Recombinant Human CTSD Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
CTSD-189H | Active Native Human Cathepsin D | +Inquiry |
CTSD-27858TH | Native Human CTSD | +Inquiry |
CTSD-26411TH | Active Native Human Cathepsin D protein | +Inquiry |
◆ Lysates | ||
CTSD-1735HCL | Recombinant Human CTSD cell lysate | +Inquiry |
CTSD-3023MCL | Recombinant Mouse CTSD cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0264 | Cathepsin D Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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