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Active Recombinant Human CTSZ Protein, His-tagged

Cat.No. : CTSZ-658H
Product Overview : Recombinant Human CTSZ Protein is produced by Baculovirus expression system. This protein is fused with a His tag.
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Description : Cathepsin Z, also known Cathepsin X and Cathepsin P, is a member of the C1 family of lysosomal cysteine proteases. It exhibits carboxy-monopeptidase and carboxy-dipeptidase activity. This protein regulates maturation of dendritic cells and plays important role in the initiation of adaptive immunity. It is also involved in tumor and immune cells as higher expression is found in tumour and immune cells of prostate and gastric carcinomas and inmacrophages of gastric mucosa. Recombinant human Cathepsin Z protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Source : Insect cell
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10 % glycerol.
Bio-activity : Specific activity is > 1,400 pmol/min/ug in which one unit will convert 1.0 pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25 centigrade.
Molecular Mass : 32.5 kDa
Protein length : 24-303 aa
AA Sequence : GLYFRRGQTC YRPLRGDGLA PLGRSTYPRP HEYLSPADLP KSWDWRNVDG VNYASITRNQ HIPQYCGSCW AHASTSAMAD RINIKRKGAW PSTLLSVQNV IDCGNAGSCE GGNDLSVWDY AHQHGIPDET CNNYQAKDQE CDKFNQCGTC NEFKECHAIR NYTLWRVGDY GSLSGREKMM AEIYANGPIS CGIMATERLA NYTGGIYAEY QDTTYINHVV SVAGWGISDG TEYWIVRNSW GEPWGERGWL RIVTSTYKDG KGARYNLAIE EHCTFGDPIV LEHHHHHH
Endotoxin : < 1.0 EU per 1 ug of protein (determined by LAL method)
Purity : > 95 % by SDS - PAGE
Notes : For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Absorbance at 280 nm)
Gene Name : CTSZ cathepsin Z [ Homo sapiens ]
Official Symbol : CTSZ
Synonyms : CTSZ; cathepsin Z; carboxypeptidase LB; cathepsin B2; cathepsin IV; cathepsin X; cathepsin Y; cathepsin Z1; CTSX; cysteine type carboxypeptidase; lysosomal carboxypeptidase B; cathepsin P; preprocathepsin P; cysteine-type carboxypeptidase; FLJ17088;
Gene ID : 1522
mRNA Refseq : NM_001336
Protein Refseq : NP_001327
MIM : 603169
UniProt ID : Q9UBR2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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