Recombinant Human CXCL1 Protein

Cat.No. : CXCL1-02H
Product Overview : Recombinant Human CXCL1 Protein was expressed in E. coli.
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  • Gene Information
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Description : Human CXCL1 is a 73 amino acid, ELR+ chemokine that belongs to the GRO isoform subset which activate the G protein-coupled receptor CXCR2. TNF-stimulated epithelial cells strongly express CXCL1 in addition to the constitutive expression by macrophages. CXCL1 is a potent chemoattractant for neutrophils and an activator of basophils.
Source : E. coli
Species : Human
Form : Lyophilized
Molecular Mass : 7.8612 kDa
Protein length : 73 amino acid
AA Sequence : ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN
Endotoxin : Endotoxin-free <0.01 EU/ug
Purity : Purity assessed by HPLC, Mass Spectrometry, and NMR
Storage : Store at -20 to -80 centigrade for 12 months; Store at 4 centigrade for 6 months; Store at RT for 1 month.
tmpcolum67 : C-X-C motif chemokine ligand 1
Gene Name : CXCL1 C-X-C motif chemokine ligand 1 [ Homo sapiens (human) ]
Official Symbol : CXCL1
Synonyms : FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
Gene ID : 2919
mRNA Refseq : NM_001511
Protein Refseq : NP_001502
MIM : 155730
UniProt ID : P09341

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Are there any therapeutic strategies targeting CXCL1? 11/17/2022

Therapeutic strategies targeting CXCL1 aim to modulate its activity in diseases like cancer and chronic inflammation.

How does CXCL1 contribute to inflammation? 05/03/2022

It mediates inflammation by promoting leukocyte migration and activation.

What role does CXCL1 play in tumor progression? 09/30/2021

In cancer, CXCL1 can promote tumor growth, metastasis, and angiogenesis.

What is the relationship between CXCL1 and angiogenesis? 04/21/2021

CXCL1 contributes to angiogenesis, supporting new blood vessel formation.

What is the primary function of CXCL1 in the immune system? 11/15/2019

CXCL1 is a chemokine that attracts neutrophils to sites of infection or injury.

In which pathological conditions is CXCL1 found to be elevated? 08/05/2018

CXCL1 levels are elevated in conditions like cancer, inflammatory diseases, and infections.

How is the expression of CXCL1 regulated in cells? 02/06/2018

CXCL1 expression is regulated by various stimuli, including cytokines and growth factors.

Customer Reviews (3)

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06/15/2020

    Efficient delivery, great service. -

    01/01/2019

      Product as described, perfect. -

      10/13/2018

        Reliable for protein work. -

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