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Recombinant Human CYP11B1 Protein, MYC/DDK-tagged, C13 and N15-labeled

Cat.No. : CYP11B1-387H
Product Overview : CYP11B1 MS Standard C13 and N15-labeled recombinant protein (NP_001021384) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 49.7 kDa
AA Sequence : MALRAKAEVCMAVPWLSLQRAQALG TRAARVPRTVLPFEAMPRRPGNRWL RLLQIWREQGYEDLHLEVHQTFQEL GPIFRYDLGGAGMVCVMLPEDVEKL QQVDSLHPHRMSLEPWVAYRQHRGH KCGVFLLNGPEWRFNRLRLNPEVLS PNAVQRFLPMVDAVARDFSQALKKK VLQNARGSLTLDVQPSIFHYTIEAS NLALFGERLGLVGHSPSSASLNFLH ALEVMFKSTVQLMFMPRSLSRWTSP KVWKEHFEAWDCIFQYGDNCIQKIY QELAFSRPQQYTSIVAELLLNAELS PDAIKANSMELTAGSVDTTVFPLLM TLFELARNPNVQQALRQESLAAAAS ISEHPQKATTELPLLRAALKETLRL YPVGLFLERVASSDLVLQNYHIPAG VLKHLQVETLTQEDIKMVYSFILRP SMFPLLTFRAINTRTRPLEQKLISE EDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 [ Homo sapiens (human) ]
Official Symbol : CYP11B1
Synonyms : CYP11B1; cytochrome P450, family 11, subfamily B, polypeptide 1; CYP11B, cytochrome P450, subfamily XIB (steroid 11 beta hydroxylase), polypeptide 1; cytochrome P450 11B1, mitochondrial; CPN1; FHI; P450C11; CYPXIB1; cytochrome P450C11; cytochrome P-450c11; cytochrome p450 XIB1; steroid 11-beta-hydroxylase; steroid 11-beta-monooxygenase; cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1; CYP11B; FLJ36771; DKFZp686B05283;
Gene ID : 1584
mRNA Refseq : NM_001026213
Protein Refseq : NP_001021384
MIM : 610613
UniProt ID : P15538

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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