Recombinant Human CYP1A1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CYP1A1-2195H |
Product Overview : | CYP1A1 MS Standard C13 and N15-labeled recombinant protein (NP_000490) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 58.2 kDa |
AA Sequence : | MLFPISMSATEFLLASVIFCLVFWV IRASRPQVPKGLKNPPGPWGWPLIG HMLTLGKNPHLALSRMSQQYGDVLQ IRIGSTPVVVLSGLDTIRQALVRQG DDFKGRPDLYTFTLISNGQSMSFSP DSGPVWAARRRLAQNGLKSFSIASD PASSTSCYLEEHVSKEAEVLISTLQ ELMAGPGHFNPYRYVVVSVTNVICA ICFGRRYDHNHQELLSLVNLNNNFG EVVGSGNPADFIPILRYLPNPSLNA FKDLNEKFYSFMQKMVKEHYKTFEK GHIRDITDSLIEHCQEKQLDENANV QLSDEKIINIVLDLFGAGFDTVTTA ISWSLMYLVMNPRVQRKIQEELDTV IGRSRRPRLSDRSHLPYMEAFILET FRHSSFVPFTIPHSTTRDTSLKGFY IPKGRCVFVNQWQINHDQKLWVNPS EFLPERFLTPDGAIDKVLSEKVIIF GMGKRKCIGETIARWEVFLFLAILL QRVEFSVPLGVKVDMTPIYGLTMKH ACCEHFQMQLRSTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CYP1A1 cytochrome P450 family 1 subfamily A member 1 [ Homo sapiens (human) ] |
Official Symbol : | CYP1A1 |
Synonyms : | CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1; CYP1, cytochrome P450, subfamily I (aromatic compound inducible), polypeptide 1; cytochrome P450 1A1; CP11; P1 450; P450 C; P450DX; CYPIA1; cytochrome P450-C; cytochrome P450-P1; cytochrome P450 form 6; xenobiotic monooxygenase; aryl hydrocarbon hydroxylase; flavoprotein-linked monooxygenase; cytochrome P1-450, dioxin-inducible; cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; AHH; AHRR; CYP1; P1-450; P450-C; |
Gene ID : | 1543 |
mRNA Refseq : | NM_000499 |
Protein Refseq : | NP_000490 |
MIM : | 108330 |
UniProt ID : | P04798 |
Products Types
◆ Recombinant Protein | ||
CYP1A1-69H | Active Recombinant Human CYP1A1 Protein | +Inquiry |
CYP1A1-2244H | Recombinant Human CYP1A1 Protein, GST-tagged | +Inquiry |
CYP1A1-2769H | Recombinant Human CYP1A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP1A1-1374R | Recombinant Rat CYP1A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP1A1-961R | Recombinant Rhesus Macaque CYP1A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CYP1A1-7126HCL | Recombinant Human CYP1A1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket