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Active Recombinant Human CYR61 Protein, Fc Chimera

Cat.No. : CYR61-895H
Product Overview : Recombinant Human CYR61 (Accession # O00622), fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived.
  • Specification
  • Gene Information
  • Related Products
Source : CHO Cells
Species : Human
Tag : Fc
Predicted N Terminal : Ala22
Form : Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.
Bio-activity : Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion. Ball, D.K. et al. (2003) Reproduction 125:271. Recombinant Human Cyr61/CCN1 Fc Chimera immobilized at 1.5 µg/mL, 100 µL/well, will mediate >25% BALB/3T3 cell adhesion (3 x 10^4 cell/well added).
Molecular Mass : Recombinant Human CYR61, Fc Chimera has a calculated MW of 66.3 kDa. In SDS-PAGE migrates as 70-75 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : CYR61 cysteine-rich, angiogenic inducer, 61 [ Homo sapiens ]
Official Symbol : CYR61
Synonyms : CYR61; cysteine-rich, angiogenic inducer, 61; IGFBP10; protein CYR61; CCN1; GIG1; IBP-10; IGFBP-10; CCN family member 1; IGF-binding protein 10; cysteine-rich, anigogenic inducer, 61; cysteine-rich heparin-binding protein 61; insulin-like growth factor-binding protein 10;
Gene ID : 3491
mRNA Refseq : NM_001554
Protein Refseq : NP_001545
MIM : 602369
UniProt ID : O00622
Chromosome Location : 1p22.3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What did recent research on CYR61 find? 10/09/2021

Recent studies have found that CYR61 plays an important role in tumor development and metastasis, especially in cancers such as non-small cell lung cancer, breast cancer, gastric cancer, and colorectal cancer.

Which drugs can inhibit the expression level of CYR61? 03/03/2021

There are currently no drugs specifically targeting CYR61, but some anti-tumor drugs can inhibit the expression level of CYR61, such as chemotherapy drugs and targeted therapy drugs.

What is the relationship between the level of CYR61 expression and patient survival? 02/08/2021

Studies have shown that high levels of CYR61 expression are associated with decreased patient survival, suggesting that it may be used as a biomarker to predict patient survival.

What signaling pathways is CYR61 involved in? 12/26/2020

CYR61 is involved in a variety of signaling pathways, including Wnt, MAPK, ERK, and PI3K.

What is the significance of regulating the expression level of CYR61 for the treatment of diseases? 06/03/2020

Regulating the expression level of CYR61 is of great significance for the treatment of diseases, especially for the treatment of cancer, and can slow down the growth and spread of tumors by inhibiting the expression level of CYR61.

How can the relationship between CYR61 expression levels and disease risk be assessed? 02/24/2020

The relationship between CYR61 expression levels and disease risk can be assessed by immunohistochemistry or western blot analysis of the patient's tissue samples.

Customer Reviews (3)

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Reviews
07/18/2022

    It has good effect and stability in gene expression regulation.

    06/04/2022

      Will not interact with other drugs, will not affect.

      07/20/2021

        The application performance is stable in common colorimetric reactions.

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