| Description : |
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
53.9 kDa |
| AA Sequence : |
MNASEFRRRGKEMVDYVANYMEGIE GRQVYPDVEPGYLRPLIPAAAPQEP DTFEDIINDVEKIIMPGVTHWHSPY FFAYFPTASSYPAMLADMLCGAIGC IGFSWAASPACTELETVMMDWLGKM LELPKAFLNEKAGEGGGVIQGSASE ATLVALLAARTKVIHRLQAASPELT QAAIMEKLVAYSSDQAHSSVERAGL IGGVKLKAIPSDGNFAMRASALQEA LERDKAAGLIPFFMVATLGTTTCCS FDNLLEVGPICNKEDIWLHVDAAYA GSAFICPEFRHLLNGVEFADSFNFN PHKWLLVNFDCSAMWVKKRTDLTGA FRLDPTYLKHSHQDSGLITDYRHWQ IPLGRRFRSLKMWFVFRMYGVKGLQ AYIRKHVQLSHEFESLVRQDPRFEI CVEVILGLVCFRLKGSNKVNEALLQ RINSAKKIHLVPCHLRDKFVLRFAI CSRTVESAHVQRAWEHIKELAADVL RAERETRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
