| Description : |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
92.2 kDa |
| AA Sequence : |
MAAAFEASGALAAVATAMPAEHVAV QVPAPEPTPGPVRILRTAQDLSSPR TRTGDVLLAEPADFESLLLSRPVLE GLRAAGFERPSPVQLKAIPLGRCGL DLIVQAKSGTGKTCVFSTIALDSLV LENLSTQILILAPTREIAVQIHSVI TAIGIKMEGLECHVFIGGTPLSQDK TRLKKCHIAVGSPGRIKQLIELDYL NPGSIRLFILDEADKLLEEGSFQEQ INWIYSSLPASKQMLAVSATYPEFL ANALTKYMRDPTFVRLNSSDPSLIG LKQYYKVVNSYPLAHKVFEEKTQHL QELFSRIPFNQALVFSNLHSRAQHL ADILSSKGFPAECISGNMNQNQRLD AMAKLKHFHCRVLISTDLTSRGIDA EKVNLVVNLDVPLDWETYMHRIGRA GRFGTLGLTVTYCCRGEEGNMMMRI AQKCNINLLPLPDPIPSGLMEECVD WDVEVKAAVHTYGIASVPNQPLKKQ IQKIERTLQIQKAHGDHMASSRNNS VSGLSVKSKNNTKQKLPVKSHSECG IIEKATSPKELGCDRQSEEQMKNSV QTPVENSTNSQHQVKEALPVSLPQI PCLSSFKIHQPYTLTFAELVEDYEH YIKEGLEKPVEIIRHYTGPGDQTVN PQNGFVRNKVTEQRVPVLASSSQSG DSESDSDSYSSRTSSQSKGNKSYLE GSSDNQLKDSESTPVDDRISLEQPP NGSDTPNPEKYQESPGIQMKTRLKE GASQRAKQSRRNLPRRSSFRLQTEA QEDDWYDCHREIRLSFSDTYQDYEE YWRAYYRAWQEYYAAASHSYYWNAQ RHPSWMAAYHMNTIYLQEMMHSNQT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
