| Description : |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
87.3 kDa |
| AA Sequence : |
MPGKLRSDAGLESDTAMKKGETLRK QTEEKEKKEKPKSDKTEEIAEEEET VFPKAKQVKKKAEPSEVDMNSPKSK KAKKKEEPSQNDISPKTKSLRKKKE PIEKKVVSSKTKKVTKNEEPSEEEI DAPKPKKMKKEKEMNGETREKSPKL KNGFPHPEPDCNPSEAASEESNSEI EQEIPVEQKEGAFSNFPISEETIKL LKGRGVTFLFPIQAKTFHHVYSGKD LIAQARTGTGKTFSFAIPLIEKLHG ELQDRKRGRAPQVLVLAPTRELANQ VSKDFSDITKKLSVACFYGGTPYGG QFERMRNGIDILVGTPGRIKDHIQN GKLDLTKLKHVVLDEVDQMLDMGFA DQVEEILSVAYKKDSEDNPQTLLFS ATCPHWVFNVAKKYMKSTYEQVDLI GKKTQKTAITVEHLAIKCHWTQRAA VIGDVIRVYSGHQGRTIIFCETKKE AQELSQNSAIKQDAQSLHGDIPQKQ REITLKGFRNGSFGVLVATNVAARG LDIPEVDLVIQSSPPKDVESYIHRS GRTGRAGRTGVCICFYQHKEEYQLV QVEQKAGIKFKRIGVPSATEIIKAS SKDAIRLLDSVPPTAISHFKQSAEK LIEEKGAVEALAAALAHISGATSVD QRSLINSNVGFVTMILQCSIEMPNI SYAWKELKEQLGEEIDSKVKGMVFL KGKLGVCFDVPTASVTEIQEKWHDS RRWQLSVATEQPELEGPREGYGGFR GQREGSRGFRGQRDGNRRFRGQREG SRGPRGQRSGGGNKSNRSQNKGQKR SFSKAFGQTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
