| Description : |
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
61.6 kDa |
| AA Sequence : |
MEDSEALGFEHMGLDPRLLQAVTDL GWSRPTLIQEKAIPLALEGKDLLAR ARTGSGKTAAYAIPMLQLLLHRKAT GPVVEQAVRGLVLVPTKELARQAQS MIQQLATYCARDVRVANVSAAEDSV SQRAVLMEKPDVVVGTPSRILSHLQ QDSLKLRDSLELLVVDEADLLFSFG FEEELKSLLCHLPRIYQAFLMSATF NEDVQALKELILHNPVTLKLQESQL PGPDQLQQFQVVCETEEDKFLLLYA LLKLSLIRGKSLLFVNTLERSYRLR LFLEQFSIPTCVLNGELPLRSRCHI ISQFNQGFYDCVIATDAEVLGAPVK GKRRGRGPKGDKASDPEAGVARGID FHHVSAVLNFDLPPTPEAYIHRAGR TARANNPGIVLTFVLPTEQFHLGKI EELLSGENRGPILLPYQFRMEEIEG FRYRCRDAMRSVTKQAIREARLKEI KEELLHSEKLKTYFEDNPRDLQLLR HDLPLHPAVVKPHLGHVPDYLVPPA LRGLVRPHKKRKKLSSSCRKAKRAK SQNPLRSFKHKGKKFRPTAKPSTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
