Recombinant Human DMRT1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DMRT1-6242H
• Product Overview: DMRT1 MS Standard C13 and N15-labeled recombinant protein (NP_068770) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.5 kDa
• AA Sequence: MPNDEAFSKPSTPSEAPHAPGVPPQ GRAGGFGKASGALVGAASGSSAGGS SRGGGSGSGASDLGAGSKKSPRLPK CARCRNHGYASPLKGHKRFCMWRDC QCKKCNLIAERQRVMAAQVALRRQQ AQEEELGISHPIPLPSAAELLVKRE NNGSNPCLMTECSGTSQPPPASVPT TAASEGRMVIQDIPAVTSRGHVENT PDLVSDSTYYSSFYQPSLFPYYNNL YNCPQYSMALAADSASGEVGNPLGG SPVKNSLRGLPGPYVPGQTGNQWQM KNMENRHAMSSQYRMHSYYPPPSYL GQSVPQFFTFEDAPSYPEARASVFS PPSSQDSGLVSLSSSSPISNKSTKA VLECEPASEPSSFTVTPVIEEDETR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DMRT1 doublesex and mab-3 related transcription factor 1 [ Homo sapiens (human) ]
• Official Symbol: DMRT1
• Synonyms: DMRT1; doublesex and mab-3 related transcription factor 1; doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis 1; DMT1; DM domain expressed in testis protein 1
• Gene ID: 1761
• mRNA Refseq: NM_021951
• Protein Refseq: NP_068770
• MIM: 602424
• UniProt ID: Q9Y5R6