Recombinant Human DTX2 Protein, MYC/DDK-tagged

• Cat.No.: DTX2-2714H
• Product Overview: Recombinant Human DTX2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 67.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DTX2 deltex homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: DTX2
• Synonyms: RNF58
• Gene ID: 113878
• mRNA Refseq: NM_001102594
• Protein Refseq: NP_001096064
• MIM: 613141
• UniProt ID: Q86UW9