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Recombinant Human DUSP13 Protein, MYC/DDK-tagged

Cat.No. : DUSP13-2716H
Product Overview : Recombinant Human DUSP13 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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Description : Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 27.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : DUSP13 dual specificity phosphatase 13 [ Homo sapiens ]
Official Symbol : DUSP13
Synonyms : BEDP; DUSP13A; DUSP13B; MDSP; SKRP4; TMDP
Gene ID : 51207
mRNA Refseq : NM_001007271
Protein Refseq : NP_001007272
MIM : 613191
UniProt ID : Q6B8I1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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