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Recombinant Human EIF2B3 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : EIF2B3-4557H
Product Overview : EIF2B3 MS Standard C13 and N15-labeled recombinant protein (NP_065098) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 50.1 kDa
AA Sequence : MEFQAVVMAVGGGSRMTDLTSSIPK PLLPVGNKPLIWYPLNLLERVGFEE VIVVTTRDVQKALCAEFKMKMKPDI VCIPDDADMGTADSLRYIYPKLKTD VLVLSCDLITDVALHEVVDLFRAYD ASLAMLMRKGQDSIEPVPGQKGKKK AVEQRDFIGVDSTGKRLLFMANEAD LDEELVIKGSILQKHPRIRFHTGLV DAHLYCLKKYIVDFLMENGSITSIR SELIPYLVRKQFSSASSQQGQEEKE EDLKKKELKSLDIYSFIKEANTLNL APYDACWNACRGDRWEDLSRSQVRC YVHIMKEGLCSRVSTLGLYMEANRQ VPKLLSALCPEEPPVHSSAQIVSKH LVGVDSLIGPETQIGEKSSIKRSVI GSSCLIKDRVTITNCLLMNSVTVEE GSNIQGSVICNNAVIEKGADIKDCL IGSGQRIEAKAKRVNEVIVGNDQLM EITRTRPLEQKLISEEDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : EIF2B3 eukaryotic translation initiation factor 2B subunit gamma [ Homo sapiens (human) ]
Official Symbol : EIF2B3
Synonyms : EIF2B3; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD); translation initiation factor eIF-2B subunit gamma; EIF 2B; EIF2Bgamma; eIF-2B GDP-GTP exchange factor subunit gamma; EIF-2B;
Gene ID : 8891
mRNA Refseq : NM_020365
Protein Refseq : NP_065098
MIM : 606273
UniProt ID : Q9NR50

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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