| Description : |
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
69 kDa |
| AA Sequence : |
MAASAKKKNKKGKTISLTDFLAEDG GTGGGSTYVSKPVSWADETDDLEGD VSTTWHSNDDDVYRAPPIDRSILPT APRAAREPNIDRSRLPKSPPYTAFL GNLPYDVTEESIKEFFRGLNISAVR LPREPSNPERLKGFGYAEFEDLDSL LSALSLNEESLGNRRIRVDVADQAQ DKDRDDRSFGRDRNRDSDKTDTDWR ARPATDSFDDYPPRRGDDSFGDKYR DRYDSDRYRDGYRDGYRDGPRRDMD RYGGRDRYDDRGSRDYDRGYDSRIG SGRRAFGSGYRRDDDYRGGGDRYED RYDRRDDRSWSSRDDYSRDDYRRDD RGPPQRPKLNLKPRSTPKEDDSSAS TSQSTRAASIFGGAKPVDTAARERE VEERLQKEQEKLQRQLDEPKLERRP RERHPSWRSEETQERERSRTGSESS QTGTSTTSSRNARRRESEKSLENET LNKEEDCHSPTSKPPKPDQPLKVMP APPPKENAWVKRSSNPPARSQSSDT EQQSPTSGGGKVAPAQPSEEGPGRK DENKVDGMNAPKGQTGNSSRGPGDG GNRDHWKESDRKDGKKDQDSRSAPE PKKPEENPASKFSSASKYAALSVDG EDENEGEDYAETRTRPLEQKLISEE DLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
