Recombinant Human ENG Protein, GST-tagged

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Recombinant Human ENG Protein, GST-tagged

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Cat.No. : ENG-3306H
Product Overview : Human ENG full-length ORF ( AAH14271, 1 a.a. - 658 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 98.12 kDa
AA Sequence : MDRGTLPLAVALLLA SCSLSPTSLAETVHC DLQPVGPERDEVTYT TSQVSKGCVAQAPNA ILEVHVLFLEFPTGP SQLELTLQASKQNGT WPREVLLVLSVNSSV FLHLQALGIPLHLAY NSSLVTFQEPPGVNT TELPSFPKTQILEWA AERGPITSAAELNDP QSILLRLGQAQGSLS FCMLEASQDMGRTLE WRPRTPALVRGCHLE GVAGHKEAHILRVLP GHSAGPRTVTVKVEL SCAPGDLDAVLILQG PPYVSWLIDANHNMQ IWTTGEYSFKIFPEK NIRGFKLPDTPQGLL GEARMLNASIVASFV ELPLASIVSLHASSC GGRLQTSPAPIQTTP PKDTCSPELLMSLIQ TKCADDAMTLVLKKE LVAHLKCTITGLTFW DPSCEAEDRGDKFVL RSAYSSCGMQVSASM ISNEAVVNILSSSSP QRKKVHCLNMDSLSF QLGLYLSPHFLQASN TIEPGQQSFVQVRVS PSVSEFLLQLDSCHL DLGPEGGTVELIQGR AAKGNCVSLLSPSPE GDPRFSFLLHFYTVP IPKTGTLSCTVALRP KTGSQDQEVHRTVFM RLNIISPDLSGCTSK GLVLPAVLGITFGAF LIGALLTAALWYIYS HTRSPSKREPVVAVA APASSESSSTNHSIG STQSTPCSTSSMA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ENG endoglin [ Homo sapiens ]
Official Symbol : ENG
Synonyms : ENG; endoglin; ORW, ORW1, Osler Rendu Weber syndrome 1; CD105; END; HHT1; CD105 antigen; ORW; ORW1; FLJ41744;
Gene ID : 2022
mRNA Refseq : NM_000118
Protein Refseq : NP_000109
MIM : 131195
UniProt ID : P17813

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