| Description : |
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
91.9 kDa |
| AA Sequence : |
MNGHISNHPSSFGMYPSQMNGYGSS PTFSQTDREHGSKTSAKALYEQRKN YARDSVSSVSDISQYRVEHLTTFVL DRKDAMITVDDGIRKLKLLDAKGKV WTQDMILQVDDRAVSLIDLESKNEL ENFPLNTIQHCQAVMHSCSYDSVLA LVCKEPTQNKPDLHLFQCDEVKANL ISEDIESAISDSKGGKQKRRPDALR MISNADPSIPPPPRAPAPAPPGTVT QVDVRSRVAAWSAWAADQGDFEKPR QYHEQEETPEMMAARIDRDVQILNH ILDDIEFFITKLQKAAEAFSELSKR KKNKKGKRKGPGEGVLTLRAKPPPP DEFLDCFQKFKHGFNLLAKLKSHIQ NPSAADLVHFLFTPLNMVVQATGGP ELASSVLSPLLNKDTIDFLNYTVNG DERQLWMSLGGTWMKARAEWPKEQF IPPYVPRFRNGWEPPMLNFMGATME QDLYQLAESVANVAEHQRKQEIKRL STEHSSVSEYHPADGYAFSSNIYTR GSHLDQGEAAVAFKPTSNRHIDRNY EPLKTQPKKYAKSKYDFVARNNSEL SVLKDDILEILDDRKQWWKVRNASG DSGFVPNNILDIVRPPESGLGRADP PYTHTIQKQRMEYGPRPADTPPAPS PPPTPVPVPVPLPPSTPAPVPVSKV PANITRQNSSSSDSGGSIVRDSQRH KQLPVDRRKSQMEEVQDELIHRLTI GRSAAQKKFHVPRQNVPVINITYDS TPEDVKTWLQSKGFNPVTVNSLGVL NGAQLFSLNKDELRTVCPEGARVYS QITVQKAALEDSSGSSELQEIMRRR QEKISAAASDSGVESFDEGSSHTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
