Recombinant Human ERBB2 protein(Domain IV), His-Avi-tagged
Cat.No. : | ERBB2-823H |
Product Overview : | Human ErbB2/Her2 Protein is expressed from mammalian with a His and Avi tag at the C-terminal. It contains Pro489-Cys630 (Domain IV). |
- Specification
- Gene Information
- Related Products
Description : | The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The Protein has a calculated MW of 18.5kDa .As a result of glycosylation, the protein migrates as 28-40kDa based on Bis-Tris PAGE. |
Protein length : | It contains Pro489-Cys630 (Domain IV). |
Endotoxin : | Less than 0.05EU per ug by the LAL method. |
Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [ Homo sapiens ] |
Official Symbol : | ERBB2 |
Synonyms : | D340 antigen; CD340; c-erb B2/neu protein; EC 2.7.10; EGFR2; ErbB2; HER2; HER-2; HER2EC 2.7.10.1; herstatin; Metastatic lymph node gene 19 protein; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; neuroblastoma/glioblastoma derived oncogene homolog; NGL; NGLTKR1; p185erbB2; Proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog); v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian) |
Gene ID : | 2064 |
mRNA Refseq : | NM_001005862 |
Protein Refseq : | NP_001005862 |
MIM : | 164870 |
UniProt ID : | P04626 |
Products Types
◆ Recombinant Protein | ||
ERBB2-288M | Recombinant Mouse ERBB2 Protein, His-tagged | +Inquiry |
ERBB2-360H | Active Recombinant Human ERBB2 Protein, His & Avi-tagged, Biotinylated | +Inquiry |
ERBB2-3444H | Recombinant Human ERBB2 Protein, GST-tagged | +Inquiry |
ERBB2-046H | Recombinant Human ERBB2 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
ERBB2-183H | Active Recombinant Human ERBB2 Protein, His-Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
ERBB2-001CCL | Recombinant Cynomolgus ERBB2 cell lysate | +Inquiry |
ERBB2-465HCL | Recombinant Human ERBB2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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