Active Recombinant Human Fas protein, Fc-tagged
Cat.No. : | Fas-026H |
Product Overview : | Recombinant Human Fas protein(Gln 26 - Asn 173), fused with Fc tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Human Fas Ligand, His Tag, premium grade at 2 μg/mL (100 μL/well) can bind Human Fas Protein, Fc Tag with a linear range of 0.3-5 ng/mL. |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminus.The protein has a calculated MW of 42.8 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Gln26-Asn173 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE.>90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please protect from light and avoid repeated freeze-thaw cycles.This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | FAS Fas (TNF receptor superfamily, member 6) [ Homo sapiens ] |
Official Symbol : | Fas |
Synonyms : | FAS; Fas (TNF receptor superfamily, member 6); APT1, FAS1, TNFRSF6, tumor necrosis factor receptor superfamily, member 6; tumor necrosis factor receptor superfamily member 6; APO 1; CD95; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; APO-1 cell surface antigen; apoptosis-mediating surface antigen FAS; tumor necrosis factor receptor superfamily, member 6; APT1; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; |
Gene ID : | 355 |
mRNA Refseq : | NM_000043 |
Protein Refseq : | NP_000034 |
MIM : | 134637 |
UniProt ID : | P25445 |
Products Types
◆ Lysates | ||
FAS-2419MCL | Recombinant Mouse FAS cell lysate | +Inquiry |
FAS-001CCL | Recombinant Cynomolgus FAS cell lysate | +Inquiry |
FAS-1139RCL | Recombinant Rat FAS cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionFAS protein plays an important role in cell signaling, it can activate downstream signaling pathways, such as death signaling pathway and survival signaling pathway, by binding to its ligand and transmitting signals.
It can provide a reference for clinical practice and guide the diagnosis, treatment and prevention of diseases by detecting the expression level of FAS protein and understanding its mechanism of action.
FAS protein-related diseases can be prevented and treated by regulating the expression level of FAS protein and inhibiting its signaling pathway.
Gene knockout or knockdown techniques can be used to study the function and mechanism of action of FAS proteins. By knocking out or knocking down the FAS gene, changes in processes such as apoptosis and immune response can be observed to further understand its function and mechanism of action.
FAS protein can bind to its ligand, activate the death signaling pathway, and induce apoptosis.
The expression level and activity of FAS protein can be measured to predict the prognosis and development trend of certain diseases.
Customer Reviews (3)
Write a reviewWhen experimenting with FAS, the results are very reproducible.
The stability of FAS products allows them to cope with different experimental conditions and modes of operation.
FAS has high specific activity and can exert strong biological effect at low concentration.
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