Recombinant Human FCGR2B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FCGR2B-3789H
• Product Overview: FCGR2B MS Standard C13 and N15-labeled recombinant protein (NP_001002275) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 33.8 kDa
• AA Sequence: MGILSFLPVLATESDWADCKSPQPW GHMLLWTAVLFLAPVAGTPAAPPKA VLKLEPQWINVLQEDSVTLTCRGTH SPESDSIQWFHNGNLIPTHTQPSYR FKANNNDSGEYTCQTGQTSLSDPVH LTVLSEWLVLQTPHPEFQEGETIVL RCHSWKDKPLVKVTFFQNGKSKKFS RSDPNFSIPQANHSHSGDYHCTGNI GYTLYSSKPVTITVQAPSSSPMGII VAVVTGIAVAAIVAAVVALIYCRKK RISALPGYPECREMGETLPEKPANP TNPDEADKVGAENTITYSLLMHPDA LEEPDDQNRITRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FCGR2B Fc fragment of IgG receptor IIb [ Homo sapiens (human) ]
• Official Symbol: FCGR2B
• Synonyms: FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32), FCG2, FCGR2; low affinity immunoglobulin gamma Fc region receptor II-b; CD32; CD32B; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); FCG2; FCGR2; IGFR2
• Gene ID: 2213
• mRNA Refseq: NM_001002275
• Protein Refseq: NP_001002275
• MIM: 604590
• UniProt ID: P31994