Recombinant Human Fibroblast Growth Factor Receptor 1(IIIb)
Cat.No. : | FGFR1-485H |
- Specification
- Gene Information
- Related Products
Cat. No. : | FGFR1-485H |
Description : | Fibroblast growth factor receptor-1 alpha (FGFR1-alpha) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGFR1-alpha is expressed in prostate luminal epithelial cells. FGFR1alpha signals are posteriorizing factors that control node regression and posterior embryonic development. FGFR1-alpha is a splice variant of FGFR1 containing the first immunoglobulin-like domain, whereas FGFR1-beta lacks this domain. The presence or absence of this N-terminal domain influences the affinity of the receptor towards aFGF and heparin. |
Source : | Mammalian cells |
Molecular Weight : | The predicted molecular weight of Recombinant Human FGF R1α (IIIb) is Mr 66 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110-120 kDa. |
State Of Matter : | Lyophilized. |
Purity : | > 95% by SDS Page and analyzed by silver stain. |
Endotoxin : | < 1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | FGFR1 fibroblast growth factor receptor 1 [ Homo sapiens ] |
Synonyms : | FGFR1; fibroblast growth factor receptor 1; CEK; FLG; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; HBGFR; N-SAM; FLJ99988; OTTHUMP00000190881; soluble FGFR1 variant 1; FMS-like tyrosine kinase 2; ydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1 |
Gene ID : | 2260 |
mRNA Refseq : | NM_015850 |
Protein Refseq : | NP_056934 |
UniProt ID : | P11362 |
Chromosome Location : | 8p12 |
MIM : | 607401 |
Pathway : | Adherens junction; MAPK signaling pathway; elanoma; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton; Axon guidance; Signaling by FGFR |
Function : | ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; transferase activity |
Products Types
◆ Recombinant Protein | ||
FGFR1-4123H | Recombinant Human FGFR1 Protein, GST-tagged | +Inquiry |
Fgfr1-4015M | Active Recombinant Mouse Fgfr1 protein(Met1-Glu376), hFc-tagged | +Inquiry |
FGFR1-5417H | Recombinant Human Fibroblast Growth Factor Receptor 1, His-tagged | +Inquiry |
FGFR1-4121H | Active Recombinant Human FGFR1 Protein, GST/His-tagged | +Inquiry |
FGFR1-4122H | Recombinant Human FGFR1 Protein | +Inquiry |
◆ Lysates | ||
FGFR1-1171CCL | Recombinant Cynomolgus FGFR1 cell lysate | +Inquiry |
FGFR1-2765HCL | Recombinant Human FGFR1 cell lysate | +Inquiry |
FGFR1-476HCL | Recombinant Human FGFR1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1590 | FGFR1 Functional Assay Kit | +Inquiry |
Kit-1557 | U2OS FGFR1 Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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