Recombinant Human GCLC Protein, MYC/DDK-tagged
Cat.No. : | GCLC-668H |
Product Overview : | Recombinant Human GCLC fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 72.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | GCLC glutamate-cysteine ligase, catalytic subunit [ Homo sapiens ] |
Official Symbol : | GCLC |
Synonyms : | GCLC; glutamate-cysteine ligase, catalytic subunit; GLCL, GLCLC; glutamate--cysteine ligase catalytic subunit; GCS; gamma-ECS; GCS heavy chain; gamma-glutamylcysteine synthetase; GCL; GLCL; GLCLC; |
Gene ID : | 2729 |
mRNA Refseq : | NM_001498 |
Protein Refseq : | NP_001489 |
MIM : | 606857 |
UniProt ID : | P48506 |
Products Types
◆ Recombinant Protein | ||
GCLC-4800H | Recombinant Human GCLC Protein, GST-tagged | +Inquiry |
GCLC-2148R | Recombinant Rat GCLC Protein, His (Fc)-Avi-tagged | +Inquiry |
GCLC-3507M | Recombinant Mouse GCLC Protein, His (Fc)-Avi-tagged | +Inquiry |
GCLC-973H | Recombinant Human GCLC Protein, His (Fc)-Avi-tagged | +Inquiry |
GCLC-1643R | Recombinant Rhesus Macaque GCLC Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GCLC-5983HCL | Recombinant Human GCLC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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