Active Recombinant Human GDF6 Protein
Cat.No. : | GDF6-050H |
Product Overview : | The mature recombinant human GDF-6 protein (336-455aa) without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. |
Source : | E. coli |
Species : | Human |
Bio-activity : | The ED50 as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is in the range of 2-3 ug/mL. |
Molecular Mass : | 14 kDa |
Product-Related Proteins : | 336-455 |
Endotoxin : | < 0.1 EU/μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | At -80 centigrade. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | PBS |
Gene Name : | GDF6 growth differentiation factor 6 [ Homo sapiens (human) ] |
Official Symbol : | GDF6 |
Synonyms : | GDF6; growth differentiation factor 6; KFM; KFS; KFS1; KFSL; SGM1; BMP13; CDMP2; SYNS4; BMP-13; growth/differentiation factor 6; bone morphogenetic protein 13; growth/differentiation factor 16 |
Gene ID : | 392255 |
mRNA Refseq : | NM_001001557 |
Protein Refseq : | NP_001001557 |
MIM : | 601147 |
UniProt ID : | Q6KF10 |
Products Types
◆ Recombinant Protein | ||
GDF6-3027H | Recombinant Human GDF6 Protein, His (Fc)-Avi-tagged | +Inquiry |
GDF6-106H | Recombinant Active Human GDF6 Protein, His-tagged(C-ter) | +Inquiry |
GDF6-2159R | Recombinant Rat GDF6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Gdf6-278M | Recombinant Mouse Gdf6 Protein, His-tagged | +Inquiry |
GDF6-188H | Active Recombinant Human GDF6 Protein (Thr336-Arg455), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
GDF6-5967HCL | Recombinant Human GDF6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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