Active Recombinant Human GNAI3 protein, GST-tagged
Cat.No. : | GNAI3-191H |
Product Overview : | Recombinant Human GNAI3(2-end) fused with GST tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Guanine nucleotide-binding proteins (G proteins) are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits, and function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. G protein subunit alpha i3 (GNAI3) stimulates the activity of receptor-regulated K+ channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 54 nmol/min/mg |
Molecular Mass : | 65 kDa |
Protein length : | 2-end |
Purity : | >80% |
Applications : | Enzyme Assay |
Stability : | 1 year at -70 centigrade date of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 [ Homo sapiens ] |
Official Symbol : | GNAI3 |
Synonyms : | GNAI3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3; guanine nucleotide-binding protein G(k) subunit alpha; 87U6; g(i) alpha-3; FLJ26559; |
Gene ID : | 2773 |
mRNA Refseq : | NM_006496 |
Protein Refseq : | NP_006487 |
MIM : | 139370 |
UniProt ID : | P08754 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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