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Active Recombinant Human HAVCR1, HIgG1 Fc-tagged

Cat.No. : HAVCR1-2312H
Product Overview : The extracellular domain of human Tim-1 (NP_036338.2) (Ser21-Gln295) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. Theencoded protein may be involved in the moderation of asthma and allergic diseases. The reference genomerepresents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAVseropositive individuals. Three transcript variants encoding the same protein have been found for this gene
Source : CHO cells
Species : Human
Tag : HIgG1 Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.
Molecular Mass : 57 KDa (monomer)
AA Sequence : Ser21-Gln295
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : HAVCR1 hepatitis A virus cellular receptor 1 [ Homo sapiens ]
Official Symbol : HAVCR1
Synonyms : HAVCR1; hepatitis A virus cellular receptor 1; HAVCR; HAVCR 1; TIM 1; TIM1; TIMD1; kidney injury molecule 1; T-cell membrane protein 1; T cell immunoglobin domain and mucin domain protein 1; TIM; KIM1; KIM-1; TIM-1; TIMD-1; HAVCR-1;
Gene ID : 26762
mRNA Refseq : NM_001099414
Protein Refseq : NP_001092884
MIM : 606518
UniProt ID : Q96D42
Chromosome Location : 5q33.2
Function : receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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