Active Recombinant Human HAVCR1, HIgG1 Fc-tagged
Cat.No. : | HAVCR1-2312H |
Product Overview : | The extracellular domain of human Tim-1 (NP_036338.2) (Ser21-Gln295) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. Theencoded protein may be involved in the moderation of asthma and allergic diseases. The reference genomerepresents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAVseropositive individuals. Three transcript variants encoding the same protein have been found for this gene |
Source : | CHO cells |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells. |
Molecular Mass : | 57 KDa (monomer) |
AA Sequence : | Ser21-Gln295 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | HAVCR1 hepatitis A virus cellular receptor 1 [ Homo sapiens ] |
Official Symbol : | HAVCR1 |
Synonyms : | HAVCR1; hepatitis A virus cellular receptor 1; HAVCR; HAVCR 1; TIM 1; TIM1; TIMD1; kidney injury molecule 1; T-cell membrane protein 1; T cell immunoglobin domain and mucin domain protein 1; TIM; KIM1; KIM-1; TIM-1; TIMD-1; HAVCR-1; |
Gene ID : | 26762 |
mRNA Refseq : | NM_001099414 |
Protein Refseq : | NP_001092884 |
MIM : | 606518 |
UniProt ID : | Q96D42 |
Chromosome Location : | 5q33.2 |
Function : | receptor activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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