Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human HAVCR2, MIgG2a Fc-tagged

Cat.No. : HAVCR2-217H
Product Overview : The extracellular domain of human Tim-3 (NP_116171.3) (Ser22-Arg200) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO celL
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins.CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokinesecretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-typehypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infectionsand the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein thatregulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotesimmunological tolerance.
Source : CHO cells
Species : Human
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its binding ability in a functional ELISA.
Molecular Mass : 48 KDa (monomer)
AA Sequence : Ser22-Arg200
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens ]
Official Symbol : HAVCR2
Synonyms : HAVCR2; hepatitis A virus cellular receptor 2; FLJ14428; Tim 3; TIM3; TIMD3; kidney injury molecule-3; T-cell membrane protein 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; KIM-3; Tim-3; TIMD-3; HAVcr-2;
Gene ID : 84868
mRNA Refseq : NM_032782
Protein Refseq : NP_116171
MIM : 606652
UniProt ID : Q8TDQ0
Chromosome Location : 5q34

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All HAVCR2 Products

Required fields are marked with *

My Review for All HAVCR2 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends