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Recombinant Human HDAC3 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : HDAC3-6182H
Product Overview : HDAC3 MS Standard C13 and N15-labeled recombinant protein (NP_003874) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 48.8 kDa
AA Sequence : MAKTVAYFYDPDVGNFHYGAGHPMK PHRLALTHSLVLHYGLYKKMIVFKP YQASQHDMCRFHSEDYIDFLQRVSP TNMQGFTKSLNAFNVGDDCPVFPGL FEFCSRYTGASLQGATQLNNKICDI AINWAGGLHHAKKFEASGFCYVNDI VIGILELLKYHPRVLYIDIDIHHGD GVQEAFYLTDRVMTVSFHKYGNYFF PGTGDMYEVGAESGRYYCLNVPLRD GIDDQSYKHLFQPVINQVVDFYQPT CIVLQCGADSLGCDRLGCFNLSIRG HGECVEYVKSFNIPLLVLGGGGYTV RNVARCWTYETSLLVEEAISEELPY SEYFEYFAPDFTLHPDVSTRIENQN SRQYLDQIRQTIFENLKMLNHAPSV QIHDVPADLLTYDRTDEADAEERGP EENYSRPEAPNEFYDGDHDNDKESD VEITRTRPLEQKLISEEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : HDAC3 histone deacetylase 3 [ Homo sapiens (human) ]
Official Symbol : HDAC3
Synonyms : HDAC3; histone deacetylase 3; HD3; RPD3; RPD3 2; SMAP45; RPD3-2;
Gene ID : 8841
mRNA Refseq : NM_003883
Protein Refseq : NP_003874
MIM : 605166
UniProt ID : O15379

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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