Recombinant Human HMGCL Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | HMGCL-4287H |
Product Overview : | HMGCL MS Standard C13 and N15-labeled recombinant protein (NP_000182) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 34.4 kDa |
AA Sequence : | MAAMRKALPRRLVGLASLRAVSTSS MGTLPKRVKIVEVGPRDGLQNEKNI VSTPVKIKLIDMLSEAGLSVIETTS FVSPKWVPQMGDHTEVLKGIQKFPG INYPVLTPNLKGFEAAVAAGAKEVV IFGAASELFTKKNINCSIEESFQRF DAILKAAQSANISVRGYVSCALGCP YEGKISPAKVAEVTKKFYSMGCYEI SLGDTIGVGTPGIMKDMLSAVMQEV PLAALAVHCHDTYGQALANTLMALQ MGVSVVDSSVAGLGGCPYAQGASGN LATEDLVYMLEGLGIHTGVNLQKLL EAGNFICQALNRKTSSKVAQATCKL TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase [ Homo sapiens (human) ] |
Official Symbol : | HMGCL |
Synonyms : | HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase; 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase; hydroxymethylglutaryl-CoA lyase, mitochondrial; HL; hydroxymethylglutaricaciduria; HMG-CoA lyase; 3-hydroxy-3-methylglutaryl-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase; mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase; |
Gene ID : | 3155 |
mRNA Refseq : | NM_000191 |
Protein Refseq : | NP_000182 |
MIM : | 613898 |
UniProt ID : | P35914 |
Products Types
◆ Recombinant Protein | ||
HMGCL-4874H | Recombinant Human HMGCL Protein, GST-tagged | +Inquiry |
Hmgcl-1136M | Recombinant Mouse Hmgcl Protein, MYC/DDK-tagged | +Inquiry |
HMGCL-2522R | Recombinant Rat HMGCL Protein, His (Fc)-Avi-tagged | +Inquiry |
HMGCL-211H | Recombinant Human HMGCL Protein, His-tagged | +Inquiry |
HMGCL-4239M | Recombinant Mouse HMGCL Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HMGCL-5475HCL | Recombinant Human HMGCL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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