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Recombinant Human HNF4A Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : HNF4A-1852H
Product Overview : HNF4A MS Standard C13 and N15-labeled recombinant protein (NP_001025174) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 48.8 kDa
AA Sequence : MVSVNAPLGAPVESSYDTSPSEGTN LNAPNSLGVSALCAICGDRATGKHY GASSCDGCKGFFRRSVRKNHMYSCR FSRQCVVDKDKRNQCRYCRLKKCFR AGMKKEAVQNERDRISTRRSSYEDS SLPSINALLQAEVLSRQITSPVSGI NGDIRAKKIASIADVCESMKEQLLV LVEWAKYIPAFCELPLDDQVALLRA HAGEHLLLGATKRSMVFKDVLLLGN DYIVPRHCPELAEMSRVSIRILDEL VLPFQELQIDDNEYAYLKAIIFFDP DAKGLSDPGKIKRLRSQVQVSLEDY INDRQYDSRGRFGELLLLLPTLQSI TWQMIEQIQFIKLFGMAKIDNLLQE MLLGGSPSDAPHAHHPLHPHLMQEH MGTNVIVANTMPTHLSNGQMSTPET PQPSPPGGSGSEPYKLLPGAVATIV KPLSAIPQPTITKQEVITRTRPLEQ KLISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : HNF4A hepatocyte nuclear factor 4 alpha [ Homo sapiens (human) ]
Official Symbol : HNF4A
Synonyms : HNF4A; hepatocyte nuclear factor 4, alpha; MODY, MODY1, TCF14; hepatocyte nuclear factor 4-alpha; HNF4; NR2A1; TCF-14; HNF-4-alpha; HNF4alpha10/11/12; transcription factor 14; transcription factor-14; transcription factor HNF-4; hepatic nuclear factor 4 alpha; nuclear receptor subfamily 2 group A member 1; TCF; MODY; MODY1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; HNF4alpha; FLJ39654;
Gene ID : 3172
mRNA Refseq : NM_001030003
Protein Refseq : NP_001025174
MIM : 600281
UniProt ID : P41235

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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