Recombinant Human HSD17B7 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HSD17B7-3193H
• Product Overview: HSD17B7 MS Standard C13 and N15-labeled recombinant protein (NP_057455) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38.2 kDa
• AA Sequence: MRKVVLITGASSGIGLALCKRLLAE DDELHLCLACRNMSKAEAVCAALLA SHPTAEVTIVQVDVSNLQSVFRASK ELKQRFQRLDCIYLNAGIMPNPQLN IKALFFGLFSRKVIHMFSTAEGLLT QGDKITADGLQEVFETNVFGHFILI RELEPLLCHSDNPSQLIWTSSRSAR KSNFSLEDFQHSKGKEPYSSSKYAT DLLSVALNRNFNQQGLYSNVACPGT ALTNLTYGILPPFIWTLLMPAILLL RFFANAFTLTPYNGTEALVWLFHQK PESLNPLIKYLSATTGFGRNYIMTQ KMDLDEDTAEKFYQKLLELEKHIRV TIQKTDNQARLSGSCLTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 [ Homo sapiens (human) ]
• Official Symbol: HSD17B7
• Synonyms: HSD17B7; hydroxysteroid (17-beta) dehydrogenase 7; 3-keto-steroid reductase; PRAP; SDR37C1; short chain dehydrogenase/reductase family 37C; member 1; 17-beta-HSD 7; estradiol 17-beta-dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 7; 17 beta-hydroxysteroid dehydrogenase type VII; short chain dehydrogenase/reductase family 37C, member 1; MGC12523; MGC75018
• Gene ID: 51478
• mRNA Refseq: NM_016371
• Protein Refseq: NP_057455
• MIM: 606756
• UniProt ID: P56937