Recombinant Human HSD3B2 protein, Myc/DDK-tagged

• Cat.No.: HSD3B2-23H
• Product Overview: Recombinant HSD3B2 protein, fused to Myc/DDK-tag at C-terminus, was expressed in HKE293T and captured through anti-DDK affinity column followed byconventional chromatography steps.

Specification

• Description: The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidativeconversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion ofketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. Thisgene is predominantly expressed in the adrenals and the gonads. Mutations in this gene areassociated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively splicedtranscript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Molecular Mass: 41.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method

Gene Information

• Gene Name: HSD3B2
• Official Symbol: HSD3B2
• Synonyms: HSD3B; HSDB; SDR11E2
• Gene ID: 3284
• mRNA Refseq: NM_000198.4
• Protein Refseq: NP_000189.1
• MIM: 613890
• UniProt ID: P26439