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Recombinant Human HSP90AA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : HSP90AA1-3853H
Product Overview : HSP90AA1 MS Standard C13 and N15-labeled recombinant protein (NP_001017963) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 98 kDa
AA Sequence : MPPCSGGDGSTPPGPSLRDRDCPAQ SAEYPRDRLDPRPGSPSEASSPPFL RRAPVNWYQEKAQVFLWHLLVSGST TLLCLWKQPFHVSAFPVTASLAFRQ SQGAGQHLYKDLQPFILLRLLMPEE TQTQDQPMEEEEVETFAFQAEIAQL MSLIINTFYSNKEIFLRELISNSSD ALDKIRYESLTDPSKLDSGKELHIN LIPNKQDRTLTIVDTGIGMTKADLI NNLGTIAKSGTKAFMEALQAGADIS MIGQFGVGFYSAYLVAEKVTVITKH NDDEQYAWESSAGGSFTVRTDTGEP MGRGTKVILHLKEDQTEYLEERRIK EIVKKHSQFIGYPITLFVEKERDKE VSDDEAEEKEDKEEEKEKEEKESED KPEIEDVGSDEEEEKKDGDKKKKKK IKEKYIDQEELNKTKPIWTRNPDDI TNEEYGEFYKSLTNDWEDHLAVKHF SVEGQLEFRALLFVPRRAPFDLFEN RKKKNNIKLYVRRVFIMDNCEELIP EYLNFIRGVVDSEDLPLNISREMLQ QSKILKVIRKNLVKKCLELFTELAE DKENYKKFYEQFSKNIKLGIHEDSQ NRKKLSELLRYYTSASGDEMVSLKD YCTRMKENQKHIYYITGETKDQVAN SAFVERLRKHGLEVIYMIEPIDEYC VQQLKEFEGKTLVSVTKEGLELPED EEEKKKQEEKKTKFENLCKIMKDIL EKKVEKVVVSNRLVTSPCCIVTSTY GWTANMERIMKAQALRDNSTMGYMA AKKHLEINPDHSIIETLRQKAEADK NDKSVKDLVILLYETALLSSGFSLE DPQTHANRIYRMIKLGLGIDEDDPT ADDTSAAVTEEMPPLEGDDDTSRME EVDTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : HSP90AA1 heat shock protein 90 alpha family class A member 1 [ Homo sapiens (human) ]
Official Symbol : HSP90AA1
Synonyms : HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock 90kD protein 1, alpha, heat shock 90kDa protein 1, alpha, HSPC1, HSPCA; heat shock protein HSP 90-alpha; FLJ31884; Hsp89; Hsp90; HSP90N; HSP 86; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kDa protein 1, alpha; renal carcinoma antigen NY-REN-38; heat shock 90kD protein, alpha-like 4; heat shock 90kD protein 1, alpha-like 4; HSPN; LAP2; HSP86; HSPC1; HSPCA; HSP89A; HSP90A; HSPCAL1; HSPCAL4;
Gene ID : 3320
mRNA Refseq : NM_001017963
Protein Refseq : NP_001017963
MIM : 140571
UniProt ID : P07900

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the relationship between HSP90AA1 protein and inflammatory diseases? 12/08/2019

HSP90AA1 proteins can participate in regulating the expression and function of inflammatory factors in the inflammatory process, which has an impact on the occurrence and development of inflammatory diseases.

What is the role of HSP90AA1 protein in immunotherapy? 10/12/2019

HSP90AA1 proteins can help immune cells fold and activate some important antigens, participate in the immune response process, and have an impact on tumor immunotherapy.

Which fuction of HSP90AA1 protein in tumor diagnosis? 04/18/2019

The expression level of HSP90AA1 protein is upregulated in some tumor cells and can serve as a potential tumor biomarker for tumor diagnosis and monitoring.

Can HSP90AA1 protein be used as a therapeutic target for inflammatory diseases? 04/08/2019

There is no clear evidence that HSP90AA1 protein can be used as a therapeutic target for inflammatory diseases, but its regulatory role in the inflammatory process may provide new ideas for the development of related therapeutic strategies.

What is the relationship between HSP90AA1 protein and tumor drug resistance? 04/04/2019

HSP90AA1 proteins can lead to the occurrence and development of tumor drug resistance by stabilizing and protecting some resistance-related proteins, such as ABC transporters.

How to use HSP90AA1 protein to develop cancer therapeutics? 01/04/2019

Inhibitors targeting HSP90AA1 proteins can be developed to interfere with their interactions with other proteins, affecting the growth and survival of tumor cells.

Customer Reviews (3)

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Reviews
04/03/2022

    This powerful biological activity of the protein combined with its high purity makes the experimental results extremely reliable.

    02/10/2020

      Application range of this protein is really wide, from the laboratory to the clinic, can see its figure, it is really rare.

      08/08/2019

        Short half-life and high clearance of recombinant proteins enable them to effectively avoid drug accumulation and side effects, and provide a strong guarantee for patient safety.

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