Active Recombinant Human HSPA5 protein, His-tagged
Cat.No. : | HSPA5-1551H |
Product Overview : | Recombinant full length (aa 1-654) human GRP78 BiP Protein with His tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 20 mM Tris-HCl, pH 7.5, 50 mM KCl, 1 mM DTT, 5 mM MgCl2. |
Bio-activity : | GRP78 has ATPase activity at the time of manufacture of 2.3 μM phosphate liberated/hr/μg protein in a 200 μl reaction at 37 centigrade (pH7.5) in the presence of 20 μl of 1 mM ATP using a Malachite Green assay. |
Molecular Mass : | 78 kDa |
Storage : | Stable for 2 years at -70 centigrade from date of shipment. Please aliquot to avoid repeated freezing and thawing. |
Gene Name : | HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [ Homo sapiens ] |
Official Symbol : | HSPA5 |
Synonyms : | HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); GRP78, heat shock 70kD protein 5 (glucose regulated protein, 78kD); 78 kDa glucose-regulated protein; BiP; immunoglobulin heavy chain-binding protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; BIP; MIF2; GRP78; FLJ26106; |
Gene ID : | 3309 |
mRNA Refseq : | NM_005347 |
Protein Refseq : | NP_005338 |
MIM : | 138120 |
UniProt ID : | P11021 |
Products Types
◆ Recombinant Protein | ||
Hspa5-238M | Recombinant Mouse Hspa5 Protein, His-tagged | +Inquiry |
HSPA5-8943H | Recombinant Human HSPA5 Protein, His-tagged | +Inquiry |
Hspa5-1067M | Recombinant Mouse Hspa5 Protein, MYC/DDK-tagged | +Inquiry |
HSPA5-068H | Active Recombinant Human HSPA5 Protein, His-tagged | +Inquiry |
HSPA5-2010M | Recombinant Mouse HSPA5 Protein (20-655 aa), His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionSome studies explore small molecules and compounds that target HSPA5 as potential therapeutic agents, but clinical applications are still under investigation.
HSPA5 is involved in various conditions, including cardiovascular diseases, diabetes, and neurodegenerative disorders.
Elevated levels of HSPA5 in certain cancers may serve as a diagnostic marker, providing information about the cellular stress response and potential malignancy.
HSPA5's involvement in the immune response suggests potential links to autoimmune disorders, but specific mechanisms are still being studied.
HSPA5 is involved in antigen presentation, linking its role in protein folding to the modulation of immune responses.
Customer Reviews (3)
Write a reviewThis level of support ensures that researchers have a seamless experience, enabling them to focus on their research goals without worrying about logistical or technical concerns.
Its versatility in various biological applications, along with its compatibility with different techniques, strongly recommend it as a preferred reagent for researchers in the field.
researchers highly appreciate HSPA5 protein for its excellent performance in ELISA assays and protein electron microscopy structure analysis.
Ask a Question for All HSPA5 Products
Required fields are marked with *
My Review for All HSPA5 Products
Required fields are marked with *
Inquiry Basket