Recombinant Human IDUA Protein, MYC/DDK-tagged

• Cat.No.: IDUA-995H
• Product Overview: Recombinant human IDUA protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 70 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: IDUA iduronidase, alpha-L- [ Homo sapiens ]
• Official Symbol: IDUA
• Synonyms: IDA; MPS1
• Gene ID: 3425
• mRNA Refseq: NM_000203
• Protein Refseq: NP_000194
• MIM: 252800
• UniProt ID: P35475