Active Recombinant Human IFNA2 Protein
Cat.No. : | IFNA2-075H |
Product Overview : | The mature recombinant human IFN-α2 protein containing 166 amino acid residues without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Specific activity is 1.86 x 108 units/mg, as determined in a cytopathic effect inhibition assay using EMC virus on A549 cells. |
Molecular Mass : | 19.4 kDa |
Endotoxin : | < 0.1 EU/μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | At -80 centigrade. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | PBS |
Gene Name : | IFNA2 interferon alpha 2 [ Homo sapiens (human) ] |
Official Symbol : | IFNA2 |
Synonyms : | IFNA2; interferon alpha 2; IFNA; IFNA2B; leIF A; IFN-alphaA; IFN-alpha-2; interferon alpha-2; Names; alpha-2a interferon; interferon alpha 2a; interferon alpha 2b; interferon alpha A |
Gene ID : | 3440 |
mRNA Refseq : | NM_000605 |
Protein Refseq : | NP_000596 |
MIM : | 147562 |
UniProt ID : | P01563 |
Products Types
◆ Recombinant Protein | ||
IFNA2-1261H | Acitve Recombinant Human IFNA2 protein(Cys24-Glu188) | +Inquiry |
IFNA2-2881H | Recombinant Human Full length IFNA2 protein(1-188 aa), C-His-tagged | +Inquiry |
IFNA2-2026R | Recombinant Rhesus Macaque IFNA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IFNA2-2270H | Recombinant Human IFNA2 Protein, His-tagged | +Inquiry |
IFNA2-10H | Active Recombinant Human IFNA2 Protein (24-188aa) | +Inquiry |
◆ Lysates | ||
IFNA2-1634MCL | Recombinant Mouse IFNA2 cell lysate | +Inquiry |
IFNA2-954CCL | Recombinant Cynomolgus IFNA2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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