Active Recombinant Human IGFBP1 Protein
Cat.No. : | IGFBP1-143H |
Product Overview : | Recombinant Human IGFBP1 was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer, 100mM NaCl, pH 7.2 |
Bio-activity : | ED50 was determined by its ability to inhibit IGF-I induced proliferation of MCF-7 is less than or equal to 0.5 ug/mL in the presence of 6 ng/ml of human IGF-I. |
Molecular Mass : | 25.4 kDa |
AA Sequence : | MAPWQCAPCSAEKLALCPPVSASCS EVTRSAGCGCCPMCALPLGAACGVA TARCARGLSCRALPGEQQPLHALTR GQGACVQESDASAPHAAEAGSPESP ESTEITEEELLDNFHLMAPSEEDHS ILWDAISTYDGSKALHVTNIKKWKE PCRIELYRVVESLAKAQETSGEEIS KFYLPNCNKNGFYHSRQCETSMDGE AGLCWCVYPWNGKRIPGSPEIRGDP NCQIYFNVQN |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Resuspend the protein in the desired concentration in proper buffer |
Gene Name : | IGFBP1 insulin-like growth factor binding protein 1 [ Homo sapiens ] |
Official Symbol : | IGFBP1 |
Synonyms : | IGFBP1; insulin-like growth factor binding protein 1; IBP1; insulin-like growth factor-binding protein 1; AFBP; alpha pregnancy associated endometrial globulin; amniotic fluid binding protein; binding protein 25; binding protein 26; binding protein 28; growth hormone independent binding protein; hIGFBP 1; IGF binding protein 1; IGF BP25; placental protein 12; PP12; IBP-1; IGFBP-1; binding protein-25; binding protein-26; binding protein-28; IGF-binding protein 1; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin; IGF-BP25; hIGFBP-1; |
Gene ID : | 3484 |
mRNA Refseq : | NM_000596 |
Protein Refseq : | NP_000587 |
MIM : | 146730 |
UniProt ID : | P08833 |
Products Types
◆ Recombinant Protein | ||
Igfbp1-988R | Recombinant Rat Igfbp1 Protein, His-tagged | +Inquiry |
Igfbp1-10568M | Recombinant Mouse Igfbp1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP1-03H | Active Recombinant Human IGFBP-1 Protein (26-259aa) | +Inquiry |
IGFBP1-4467M | Recombinant Mouse IGFBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Igfbp1-1226M | Recombinant Mouse Igfbp1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
IGFBP1-612H | Native Human Insulin-like Growth Factor Binding Protein 1 | +Inquiry |
◆ Lysates | ||
IGFBP1-1482CCL | Recombinant Cynomolgus IGFBP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIGFBP1 influences the progression of certain cancers, particularly those sensitive to hormonal regulation.
Changes in IGFBP1 expression contribute to the aging process and the development of age-related diseases.
IGFBP1 is important for fetal growth and development, regulating growth factor activity during pregnancy.
IGFBP1 affects muscle growth and regeneration, playing a role in conditions involving muscle wasting.
IGFBP1 impacts cardiovascular health, influencing factors like blood vessel growth and atherosclerosis development.
IGFBP1 plays a crucial role in glucose metabolism and insulin sensitivity, impacting overall metabolic health.
IGFBP1 modulates the availability and activity of IGFs, affecting growth and metabolic functions in various tissues.
Customer Reviews (3)
Write a reviewPrecise antibody validation, enhances immunoprecipitation studies.
Efficient protein purification, delivers high yield and purity.
Dependable expertise in protein engineering, unmatched quality.
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